Symbol Name ID |
Stat3
signal transducer and activator of transcription 3 MGI:103038 |
Darker colors indicate more annotations |
Human Phenotypes | Vascular dilatation |
Vasculitis |
Raynaud phenomenon |
Erythema |
Disease(s) Associated with STAT3 | ||||
Behcet's disease | ||||
hyper IgE recurrent infection syndrome 1 | ||||
rheumatoid arthritis |
Mouse Phenotypes | abnormal lung vasculature morphology |
abnormal angiogenesis |
abnormal myocardial fiber morphology |
enlarged heart |
increased heart left ventricle size |
dilated heart left ventricle |
cardiac fibrosis |
dilated heart |
abnormal cardiovascular system physiology |
decreased cardiac muscle contractility |
abnormal heart echocardiography feature |
increased cardiomyocyte apoptosis |
cardiomyopathy |
congestive heart failure |
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Availability | Mouse Genotype | ||||||||||||||
Stat3tm1Vpo/Stat3tm1Vpo Tg(Myh6-cre)2182Mds/0 (conditional) |
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Stat3tm2Aki/Stat3tm2Aki Tg(SFTPC-rtTA)5Jaw/0 Tg(tetO-cre)1Jaw/0 (conditional) |
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Stat3tm1Vpo/Stat3+ Tg(Myh6-cre)2182Mds/0 (conditional) |
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Stat3tm1Xyfu/Stat3+ Tg(Myh6-cre)2182Mds/0 (conditional) |
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Stat3tm1Xyfu/Stat3tm1.1Xyfu Tg(Myh6-cre)2182Mds/0 (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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